Abacavir hydroxyacetate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Abacavir hydroxyacetate 是一个具有口服活性的 IL-20 和 PRINS 的抑制剂。Abacavir hydroxyacetate 作为免疫调节剂，降低牛皮癣的增殖率。Abacavir hydroxyacetate 可用于炎症型皮肤病的研究。

Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems.

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Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice.Animal Model:6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue Dosage:10 and 20 mg/kg Administration:Oral gavage; 10-20 mg/kg once Result:Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis.

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Microbiology/Virology

HIV

HIV Protease

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1446418-48-9

344.37

C16H20N6O3

>98% (HPLC)

In Vitro:?DMSO 中的溶解度 : ≥ 100 mg/mL (290.39 mM )

Nc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](COC(=O)CO)C=C3)c2n1

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(-20℃)

With Ice Pack

≥ 2 years